Situated within the Australian Botanic Garden in Mount Annan, Plantbank as a scientific hub for native plant conservation under the Royal Botanic Gardens and Domain Trust.

The project houses the Trust's seed bank and specialised research labs. and is is positioned globally as a symbol of the preservation of the natural cycle from the germination of seed to the propagation of forests, and it is a partner of the Kew Garden's Millennium Seed Bank Partnership.

Its design integrates with the surrounding Cumberland Plain forest, reflecting Australia's relationship with its cultivated land.

Visitors are guided through interpretive displays linking the external courtyard to internal research areas. Clear-glazed labs allow observation of ongoing activities, culminating in a multipurpose room for seminars and events.